Inhibition of basic fibroblast growth factor-induced growth promotion by overexpression of syndecan-1.
نویسندگان
چکیده
منابع مشابه
Soluble syndecan-1 and serum basic fibroblast growth factor are new prognostic factors in lung cancer.
Syndecan-1 is a ubiquitous and multifunctional extracellular matrix proteoglycan,which mediates basic fibroblast growth factor (bFGF) binding and activity. Shedding of syndecan-1 ectodomain from the plasma membrane is highly regulated. We evaluated the influence of soluble syndecan-1 and serum bFGF determined by ELISA on outcome in 184 lung cancer patients (non-small cell lung cancer, n = 138; ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1993
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(20)80513-4